Acta Pharm. 48 (1998) 119-126

Original scientific paper  
 

The essential oils of Thymus balcanus, T. ciliatopubescens and T. pseudo-atticus from Macedonia

SVETLANA KULEVANOVA,1* MIHAILO RISTIC,2   and   TRAJCE STAFILOV3

1Institute of Pharmacognosy, Faculty of Pharmacy, 91000 Skopje, Republic of Macedonia 2Institute for Medicinal Plant Research "Dr. Josif Pancic", 11000 Belgrade, FR Yugoslavia, 3Institute of Chemistry, Faculty of Natural Sciences, 91001 Skopje, Republic of Macedonia 
Received April 21, 1998      Accepted May 26, 1998

Essential oil composition of Thymus balcanus, T. ciliatopubescens and T. pseudo-atticus from Macedonia was examined by analytical GC and GC-MS technique. More than sixty peaks were separated in each of the oils. Thirty to forty peaks were identified which represented 81-87 % of the oils. The main components in T. balcanus essential oil were trans-caryophyllene (22.42%), beta-pinene (12.48%) and alfa-pinene (5.64%). Higher amount of e-citral has been found as well (4.95%). The main component in T. ciliatopubescens essential oil was 1,8-cineole (18.00%) followed by alfa-pinene (8.82%), camphene, linalool, camphor, trans-caryophyllene and beta-nerolidol. For T. pseudo-atticus, the most important constituents were exo- and endo-borneol (4.97 % and 14.86 %, respectively). In this oil, fraction of sesquiterpens was also high with trans-caryophyllene (10.45%), beta-cubebene (9.95%) and beta-nerolidol (4.44%) being the most abundant. These three taxa of genus Thymus in the flora of the Republic of Macedonia represented nonphenolic types of Thymus containing essential oils with trace amounts of phenols (thymol and carvacrol).


Keywords: Thymus, T. balcanus, T. ciliatopubescens, T. pseudo-atticus, essential oil, composition, GC and GC-MS

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